Is it safe to use Vaseline on Eyelids? Petroleum jelly is a thick jelly that creates a moisture barrier, helping to trap moisture in the skin and protect the skin from the elements. Unless a person has an allergy or finds petroleum jelly uncomfortable, it is safe to use Vaseline on the eyelids. Keep reading to learn more about the safety and effectiveness of using Vaseline on the eyelids. Vaseline can help with a number of dry eyelid conditions. People who notice that their skin is dry or irritated during the dry, cold winter months can use it to prevent moisture loss from the eyelids. Some people also use it as a moisturizer to reduce the risk of wrinkles, or as a supplement to traditional eye creams. Some doctors also recommend Vaseline for specific dry eye conditions. It may help with blepharitis, which causes dry and irritated eyelids, as well as dysfunction in the meibomian glands that lubricate the eyes. Petroleum jelly from Vaseline can also help keep wounds moist. This may help